Acceptance and willingness to purchase a hypothetical COVID-19 vaccine in a region under Shariah law: A cross-sectional study in Aceh, Indonesia

Authors

  • Muhammad A. Rayhan School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia
  • Mudatsir Mudatsir Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia https://orcid.org/0000-0002-5643-9384
  • Nurjannah Nurjannah Department of Public Health, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia https://orcid.org/0000-0002-1485-4694
  • Ichsan Ichsan Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Tsunami and Disaster Mitigation Research Center (TDMR), Universitas Syiah Kuala, Banda Aceh, Indonesia
  • Mehrdad Amir-Behghadami Iranian Center of Excellence in Health Management, Department of Health Service Management, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran https://orcid.org/0000-0001-6723-6438
  • Yousef S. Khader Jordan University of Science and Technology, Irbid, Jordan https://orcid.org/0000-0002-7830-6857
  • Ai Koyanagi Research and Development Unit, Parc Sanitari Sant Joan de Déu, ICREA, CIBERSAM, ISCIII, Barcelona, Spain https://orcid.org/0000-0002-9565-5004
  • Ranjit Sah Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu Nepal https://orcid.org/0000-0002-2695-8714
  • Sandro G. Viveiros-Rosa Pharmacy Division, Instituto Nacional da Propriedade Industrial, Rio de Janeiro, Rio de Janeiro, Brazil https://orcid.org/0000-0002-5644-7181
  • Mohammed A. Mamun Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh; CHINTA Research Bangladesh, Dhaka, Bangladesh
  • Yohannes K. Lemu Department of Health, Behavior and Society, Faculty of Public Health, Jimma University, Ethiopia
  • Assarag Bouchra National School of Public Health, Rabat, Morocco
  • Laure SG. Linguissi Institut National de Recherche en Science de la Santé, Brazzaville, Republique of Congo https://orcid.org/0000-0002-7815-6465
  • Aamer Ikram National Institutes of Health, Islamabad, Pakistan https://orcid.org/0000-0002-6440-750X
  • Dina E. Sallam Pediatrics and Pediatric Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt https://orcid.org/0000-0003-4684-229X
  • Konstantinos Parperis Department of Internal Medicine, University of Cyprus Medical School, Nicosia, Cyprus
  • Uwe Wollina Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
  • Marius Rademaker Clinical Trials New Zealand, Hamilton, New Zealand https://orcid.org/0000-0003-3393-6748
  • Sandro Vento Faculty of Medicine, University of Puthisastra, Phnom Penh, Cambodia https://orcid.org/0000-0003-0084-4062
  • Said Usman Department of Public Health, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia https://orcid.org/0000-0002-8579-2769

DOI:

https://doi.org/10.52225/narra.v2i2.85

Keywords:

Acceptance, vaccine, COVID-19, Syariah law, willingness to purchase

Abstract

Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to determine the acceptance of and willingness to purchase a hypothetical COVID-19 vaccine in the general population of Aceh, a holistic Shariah law implementation province in Indonesia. An online cross-sectional study was conducted using a quota sampling technique between 1 to 24 September 2021. To determine hypothetical vaccine acceptance, respondents were asked if they were willing to accept vaccines with combinations of either 50% or 95% effectiveness and either 5% or 20% risk of adverse effects. Willingness to purchase was assessed by asking whether the participants would pay for such vaccines at certain price points. Logistic regression analysis was used to assess the associated determinants. Out of 377 respondents included in the final analysis, 86.5% were willing to accept a COVID-19 vaccine with 95% effectiveness and 5% adverse effects. The acceptance rate dropped to 45.1% if the risk of adverse effects was 20%. Vaccines with 50% effectiveness and 5% adverse effects were acceptable to 42.2% but the acceptance went down to 17.2% if the risk of adverse effects increased to 20%. Multivariate analysis found that men were twice as likely to accept a vaccine with 95% effectiveness and 5% adverse effects compared to females (aOR: 2.01; 95% CI 1.05–3.86). We found that 156/377 (41.3%) of respondents were willing to purchase a COVID-19 vaccine and of these participants 71.1% were willing to pay between Indonesian Rupiah (IDR) 50,000–150,000 (US$ 3.33–10.00). In conclusion, the acceptance rate of a hypothetical COVID-19 vaccine varied based on effectiveness and the risk of adverse effects.

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